NUCLIO is a non-profitable association of professional astrophysicists and amateur astronomers devoted to public outreach and education. It is also an official training center recognized by the Ministry of Education of Portugal. NUCLIO’s activities include: training teachers in the use of new technologies, promotion of real research in classroom where students are introduced to the scientific methods using robotic telescopes and data mining astronomical databases, providing Astronomy and Astrophysics courses for teachers and the general public. In the last years NUCLIO gained important expertise in the use of serious games for science education and the integration of real science experiences in classroom environment, for example, the search for asteroids, the use of robotic telescopes, etc.